Overview
- We offer a selection of fluorescent microscopes and analysis workstations including
- Several confocal microscopes for 3D optical slicing
- Several widefield deconvolution microscopes for live imaging and 3D digital slicing
- High-capacity fluorescent slide scanner
- OMX superresolution microscope
- High-powered workstations with commercial analysis software
Confocal microscopy is not always the right choice for imaging! Please schedule a chat with us to determine the best microscope for your experiments.
Fluorescence Microscopes
TissueFAXS SL Fluorescent Slide Scanner
- Rapid fluorescent scanning of fixed tissues
- Up to 7 fluorescent tags
- 120 slide loader
DeltaVision Ultra Microscope for Well-plates
- Best for live cell imaging in well-plates
- Inverted microscope with XYZ nano-motion stage and environmental chamber
- Solid state illumination module
- Ultimate Focus for long-term observation
- SoftWorx deconvolution software
DeltaVision Microscope with Ultimate Focus and TIRF module
- Best for live cell imaging, photokinetics experiments and TIRF imaging
- Inverted microscope with XYZ nano-motion stage and environmental chamber
- Solid state illumination module
- Ultimate Focus for long-term observation
- Four laser TIRF / Photokinetics module
- SoftWorx deconvolution software
DeltaVision-OMX Super-Resolution Microscope
- Best for imaging thin samples
- Experimental microscope (OMX) with XYZ nano-motion stage
- Structured Illumination with four lasers and three cameras
- Heated stage available
- Ring-TIRF illumination mode
- SoftWorx SIM reconstruction processing software
Confocal Microscopes
NEW Evident FV4000 Multiphoton and Confocal Microscope
- Fast laser scanning confocal with 5 standard laser lines out to Cy7
- Multi-photon mode for in-vivo imaging
- Low-noise photon counting detectors
- Silicone (Si) oil immersion objectives for deeper imaging in tissues
- Heated environmental chamber for live animal or cell imaging
Leica SP8 Spectral Confocal Microscope
- Best for imaging live or fixed thick samples and for Intravital Imaging
- Leica inverted DMi8 microscope with heated & CO2 environmental chamber
- White-light laser and 2 traditional lasers for tunable excitation
- One PMT and 3 high-sensitivity detectors for tunable emission filters
- Transmitted light detection
Nikon A1R Ultra-Fast Spectral Scanning Confocal Microscope
Best for imaging live/fixed thick samples
- Nikon inverted microscope with automated stage and environmental chamber
- Four-channel confocal with optional 32-channel detector
- Transmitted light detector
- Standard epifluorescence mode with camera
Olympus FV1200 Laser Scanning Confocal Microscope
- Best for imaging live/fixed thick samples
- Olympus inverted IX83 microscope with heated and CO2 stage incubator
- Five laser lines with three PMTs and two high sensitivity detectors
- Transmitted light detection
- Olympus software
Image processing workstations/computers
Nemo Imaris Workstation
- 3D workstation with ImageJ and Imaris 3D software for image processing
Marlin StrataQuest Workstation
- 2D workstation with StrataQuest for whole-slide image analysis
- Paired with TissueFAXS Slide Scanner
Other Nearby Core Microscopes
The Microscopy Core does not train on or schedule these instruments. Contacts are listed for each instrument.
Operetta CLS Confocal Screening Microscope
- Contact the High Throughput Sciences Core
- Spinning Disk Confocal Microscope
- Includes 10x, 20x, 40x Water Immersion Objective
- BL2 capable
- Built-in analysis software
- Robotic plate loader for integration into workflows
Incucyte S3 Screening Microscope
- Contact the Nanowell Cytometry Core
- 4X, 10X, 20X objectives
- Two-color Green|Red plus HD phase contrast imaging
- Holds up to 6 plates
- BL2 capable
- Built-in analysis software
Nanolive 3D Cell Explorer
- Contact the Nanowell Cytometry Core
- Quantitative interference/phase imaging for label-free imaging
- Simultaneous Fluorescence Imaging
- Up to 96-well plate
- BL2 capable
- Built-in analysis software
W.M. Keck Microscopy Innovation Center at the Whitehead Institute
- Contact the Keck facility for more information
- Several light microscopes, including widefield fluorescence, confocal, and super-resolution options
Decommissioned Microscopy Core Instruments
for reference only
DECOMMISSIONED Olympus FV1000 Multiphoton Laser Scanning Confocal Microscope
- Best for imaging live/fixed thick samples and intravital imaging
- Olympus inverted IX81 microscope with heated and CO2 stage incubator, MaiTai laser, four photomultiplier detectors
- Olympus software
DECOMMISSIONED Nikon Spinning-Disk Confocal Microscope with TIRF module
- Nikon inverted microscope with XYZ stage with perfect focus for Z stability
- Spinning disk confocal and widefield camera modes
- NOTE: Confocal mode has a small field-of-view and is primarily for live cell imaging on thicker samples. It is not intended for scanning large samples.
- TIRF excitation arm
- Standard epifluorescence mode with camera