The High Throughput Sciences Core provides automated screening capability to KI and MIT researchers, as well as access to curated small molecule and lentiviral shRNA (RNAi) libraries. The facility is equipped with an Arrayscan automated high content screening microscope, Tecan Evo liquid handlers, plate washers, automated micoplate centrifuges, an automated plate reader, high throughput flow cytometer, and automated CO2 incubators. Most instruments can be used in either walk-up or automated modes using our robot arms for general screening or plate preparation.
The facility provides assay development and screening services in both BL2 and BL2+ space, as well as consultation and training for researchers with specific needs or challenging problems.
Access is available to all members of the MIT community, to the extent permitted by available capacity. Priority access is given to KI members and NCI-funded research projects. In special circumstances, access may be available to non-MIT users (details available on request from the Core Scientific Director Jaime Cheah).
The High Throughput Sciences Core is supported in part by funding provided to the Koch Institute from a National Cancer Institute Cancer Center Support Grant.