Multi-modal data generation and high-content imaging & analysis​

Revvity Operetta CLS High-Content Microscope

• 5X to 63X magnification
• 8 excitation/emission filters
• Up to 1536-well plates
• LED & environmental controls for live-cell imaging
• Real-time image analysis
   

Tecan Spark Cyto Plate Reader

• Flexible wavelength selection
• Absorbance, luminescence, fluorescence intensity (top and bottom reading), TRF, TR-FRET, fluorescence polarization
• AlphaScreen and AlphaLISA technology
• Cell imaging: Brightfield and fluorescence (up to 4 channels) at 2/4/10X magnification.
• Confluence/Viability analysis
• Up to 1536-well plates

Liquid handling for combinatorial screening and less reagent usage​

Labcyte Echo 650

• Tip-less contact-free acoustic dispenser
• Nanoliter volumes (2.5nL per droplet)
• Combinatorial screens and cherry picking

Liquid Handling Decks In Baker Hood (HEPA) Enclosures

• Small molecule library arraying and cherry picking
• Automated cell plating, administration and removal of compounds

Tecan Evo 100

• 96-channel pipetting head and plate gripper
• Integrated automated CO2 incubator

Integra Assist Plus

• 8-channel and 12-channel pipettes
• 1-channel for cherry picking and randomization
• Modules for plate tilting, snap-cap tubes, passive cooling
• User-friendly software for walk-up use

Integrated Robotic Automated Assay Platform

• Tecan Evo 150 liquid handling deck for compound and reagent delivery
• BioTek 406 plate washer (cell plating and washing, ELISA-type assays)
• Automated microplate centrifuge
• Liconic STR 240 incubator
• HighRes AmbiStore plate stacker
• Integrated with Tecan Spark Cyto Plate Reader and Operetta CLS High-Content Imager

BL2+ Screening Platform

• BL2+ cell culture hoods and 4 HeraCell incubators