Services

Assay development and screening

• Small molecule or lentiviral screening, including combination experiments
• Cell-based assays (e.g. cytotoxicity, qPCR prep, etc)
• Biochemical assays
• Alphascreen/AlphaLISA
• ELISA
• High content/high throughput imaging in plate and slide format
• General liquid handling (plating, compound delivery, serial dilutions, plate washing, etc.)
• 96 or 384 well formats available for most screens
• Both high throughput primary screens as well as lower throughput assays for follow-up studies
• High throughput Western Blot detection

Additional Services

• Mycoplasma testing (now available through the Preclinical Modeling Facility)
• Cell line expansion, distribution and repository (MIT community only; now available through the Preclinical Modeling Facility)
• High throughput Chromatin Immunoprecipitation (ChIP) prep (from tissue or cells)
• Discounted consumables (plates, media, common reagents, tips) ~ not currently available
• BL2+ resources, including shared workspace, training, equipment and consumables

Technical Expertise

• Selection of assay and screening formats, assay development and optimization
• Consulting services for researchers with specific automation or liquid handling needs
• Tissue culture consultation
• Engineering consultation